Which Two Compounds Of A Amanita Muscaria Are Toxic

When it comes to toxic mushrooms, the Amanita muscaria is one of the most infamous. As a mushroom growing enthusiast, I believe it’s crucial to understand the compounds that make this fungus toxic. The two primary compounds responsible for the toxicity of Amanita muscaria are muscimol and ibotenic acid.


Muscimol is a psychoactive compound found in Amanita muscaria. It acts as a potent agonist of the GABAA receptors in the central nervous system. This means that muscimol has the ability to affect the brain and cause hallucinations, delirium, and a range of other neurological symptoms. In my opinion, this compound’s impact on the human mind makes it especially dangerous.

Ibotenic Acid

Another toxic compound in Amanita muscaria is ibotenic acid. This compound is a neuroexcitatory amino acid, which means that it stimulates the central nervous system. Upon ingestion, ibotenic acid is converted to muscimol, resulting in similar neurological effects. However, ibotenic acid itself can lead to symptoms such as nausea, vomiting, and muscle twitching.

In my experience, the combination of muscimol and ibotenic acid in Amanita muscaria makes it a potent and dangerous mushroom if ingested unknowingly. As a mushroom cultivator, it’s important to be able to identify these compounds and understand their potential risks.


Understanding the toxic compounds in Amanita muscaria, particularly muscimol and ibotenic acid, is essential for anyone interested in mushroom foraging or cultivation. These compounds can have profound effects on the human body and mind, and it’s crucial to exercise caution and proper knowledge when dealing with such mushrooms. As a mushroom enthusiast, I urge fellow hobbyists to prioritize safety and education in their mycological pursuits.